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MR Spectroscopy (MRS) Analysis

Automated metabolite quantification from single-voxel and multi-voxel MRS acquisitions — delivering absolute concentration estimates and quality metrics with no manual spectral fitting required.

Module Overview

The MR Spectroscopy module automates the full processing chain from raw FID signal to quantified metabolite concentrations. The built-in basis set library covers the major proton MRS metabolites at both 3T and 7T, and the fitting engine handles frequency drift, phase errors, and residual water signals automatically — eliminating the need for expert manual spectral processing.


Key Capabilities

  • 1

    Fully automated metabolite quantification for key brain metabolites: NAA, Cho, Cr, mI, Glu, Gln, GABA — with absolute and ratio-based outputs

  • 2

    Single-voxel (SVS) and multi-voxel (CSI/MRSI) acquisition support; automatic voxel placement quality check and tissue composition correction

  • 3

    Linewidth, SNR, and water suppression quality metrics automatically flagged before fitting to ensure reliable quantification

  • 4

    LCModel-compatible basis set fitting with uncertainty estimates (Cramér-Rao lower bounds) reported per metabolite


Technical Specifications

Supported sequencesPRESS, STEAM, MEGA-PRESS, sLASER
Acquisition typeSVS (single-voxel), CSI / MRSI (multi-voxel)
Field strengths3T and 7T MRI systems
Input formatsDICOM MRS, Philips .spar/.sdat, Siemens .rda, GE .7
MetabolitesNAA, Cho, Cr, mI, Glu, Gln, GABA, GSH, Lac
OutputConcentration table (CSV), spectra overlay PDF, LCModel output
Processing time< 2 min per SVS voxel; < 15 min for MRSI grid

AI Automation

An AI pre-processing stage corrects frequency and phase drifts, removes lipid contamination, and assesses spectral quality before the fitting algorithm runs. This eliminates the most common sources of quantification error and removes the need for interactive spectral pre-processing — dramatically reducing expert time per subject while improving inter-site reproducibility.

Interested in the MRI Analysis Service?

Speak with our team about a pilot programme or custom integration.

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